The year 2025 brought several influential cardiovascular studies to light, and among the most promising was the DapaTAVI trial. This randomized, open-label trial explored the impact of dapagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, in a population often seen as high-risk … Read More
Cardiovascular Disease
WARRIOR Trial: Women’s Ischemia Trial, Treating Non-Obstructive Coronary Artery Disease
In the ever-evolving landscape of cardiovascular research, the WARRIOR trial—short for Women’s Ischemia Trial to Reduce Events in Non-Obstructive CAD—has emerged as a pivotal investigation into how best to treat women with ischemia and no obstructive coronary artery disease (INOCA). … Read More
API-CAT Trial: Evaluating Low-Dose Apixaban for Cancer-Associated Thrombosis
API-CAT Trial: Evaluating Low-Dose Apixaban for Cancer-Associated Thrombosis Introduction The API-CAT trial is a groundbreaking study designed to evaluate whether a reduced dose of apixaban (2.5 mg twice daily) is as effective as the standard full-dose regimen (5 mg twice … Read More
BASIL-3 Trial: Evaluating Endovascular Strategies in Severe Leg Ischaemia
Staying up to date with landmark clinical trials is essential for evidence-based patient care, especially in fields like vascular surgery and interventional cardiology. The recently published BASIL-3 trial sheds light on the best endovascular approach for patients with chronic limb-threatening … Read More
Aortic Stenosis Severity Algorithm
Aortic Stenosis Severity Algorithm (ACC/AHA 2020 Guidelines) Step 1: Assess Aortic Valve Morphology and Function Step 2: Quantify AS Severity (Echocardiographic Parameters) Severity AVA (cm²) Mean Gradient (mmHg) Peak Velocity (m/s) Dimensionless Index (DI) Mild >1.5 <20 <3.0 >0.5 Moderate … Read More
IVUS-ACS Trial: Intravascular Ultrasound vs. Angiography for PCI in Acute Coronary Syndromes
IVUS-ACS Trial Summary Introduction In the management of acute coronary syndrome (ACS), optimal guidance for percutaneous coronary intervention (PCI) remains a critical factor in improving patient outcomes. The IVUS-ACS trial, a large, multicenter, randomized study, investigates whether intravascular ultrasound (IVUS)-guided … Read More
VT vs. SVT with Abberation Infographic
VT vs SVT with Aberration: A Quick Interpretation Guide Introduction Distinguishing ventricular tachycardia (VT) vs supraventricular tachycardia (SVT) with aberrancy is a critical skill in electrophysiology and emergency medicine. Misdiagnosis can lead to inappropriate treatment and adverse outcomes. This blog … Read More
TIME Trial: Evening versus morning dosing of usual antihypertensives
TIME StudyHypertension Treatment in Morning versus Evening Objective:To determine whether evening dosing of antihypertensive medication improves major cardiovascular outcomes compared to morning dosing in patients with hypertension. Study Design: Participants: Primary Endpoint: Results: Conclusion:Evening dosing of antihypertensive medication did not … Read More
STOPDAPT-2 ACS: Clopidogrel Monotherapy after ACS
Visual Abstract Summary for the STOPDAPT-2 ACS Trial Question Is 1–2 months of dual antiplatelet therapy (DAPT) followed by clopidogrel monotherapy noninferior to 12 months of DAPT with aspirin and clopidogrel in patients with acute coronary syndromes (ACS)? Design Key … Read More
ARIES-HM3 Trial: Aspirin + VKA in LVAD
Visual Abstract Summary for the ARIES-HM3 Trial Question Can aspirin be safely excluded from an antithrombotic regimen, including a vitamin K antagonist (VKA), in patients with a fully magnetically levitated LVAD, and does this reduce nonsurgical bleeding complications? Design Key … Read More