SECURE Trial Summary: Polypill Strategy in Secondary Cardiovascular Prevention
2022 SECURE TRIAL Polypill Strategy in Secondary Cardiovascular Prevention Phase 3, randomized, controlled clinical trial Objective: To evaluate the effect of polypill that includes key...
ARREST Trial: ECMO-facilitated Resuscitation in Refractory Cardiac Arrest
2020 ARREST 2020 TRIAL M Advanced reperfusion strategies for patients with out-of hospital cardiac arrest (OHCA) and refractory ventricular fibrillation (VF) Phase 2, single center,...
EMPULSE Trial Summary: Empagliflozin in Acute Heart Failure
2021 EMPULSE TRIAL Empagliflozin in patients hospitalized for Acute Heart Failure Randomized, parallel trial Objective: To evaluate empagliflozin compared with placebo among patients with acute...
AVATAR Trial Summary: AVR in Asymptomatic Severe Aortic Stenosis
2021 AVATAR TRIAL M Aortic Valve replacement versus Conservative treatment in asymptomatic severe Aortic Stenosis Parallel, Randomised controlled trial Objective: To evaluate aortic valve replacement...
PALACS Trial Summary: Posterior Left Pericardiotomy for Post-op AFib
2021 PALACS TRIAL M Posterior left pericardiotomy for the prevention of postoperative atrial fibrillation after cardiac surgery Randomized, parallel, stratified, single-centre study Objective: To evaluate...
ANTHARTIC Trial Summary: Prevention of Ventilator-Associated Pneumonia after Cardiac Arrest
2019 ANTHARTIC TRIAL M Prevention of early Ventilator-Associated Pneumonia after cardiac arrest Multicentre, randomised, double-blind, placebo-controlled Objective: To investigate whether in post out-of-hospital cardiac arrest...
VAM-IHCA Trial Summary: Vasopressin and Methylprednisolone on ROSC after Cardiac Arrest
2021 VAM-IHCA TRIAL M Effect of Vasopressin and Methylprednisolone vs Placebo on Return of Spontaneous Circulation in Patients with In-Hospital Cardiac Arrest Multicenter, randomized, double-blind,...
ATACAS Trial Summary: Tranexamic Acid in Coronary Artery Surgery
2017 ATACAS TRIAL: Tranexamic Acid in patients undergoing coronary artery surgery Multicenter,2×2 factorial design, double-blind, randomized controlled trial Objective: To evaluate death risk and thrombotic...
TRANSFER AMI Trial Summary: Early Angioplasty after Fibrinolysis for Acute MI
2009 TRANSFER-AMI trial: Routine Early Angioplasty after Fibrinolysis for Acute Myocardial Infarction Multicenter, randomized, non-blinded, parallel Assignment Objective: To assess outcomes in patients with AMI...
DISCHARGE Trial Summary: CT or Angio in Stable Chest Pain
2022 DISCHARGE TRIAL Summary: CT or Invasive Coronary Angiography in Stable Chest Pain- Pragmatic, randomized controlled trial- Objective: To evaluate computed tomography (CT) compared with...