MIDAS Trial Summary: Midodrine for Vasopressor Weaning
2020 MIDAS TRIAL: Effect of midodrine versus placebo on time to vasopressor discontinuation in patients with persistent hypotension in the intensive care unit Multi-centre, randomised,...
EAT-ICU Trial Summary: Early Goal-Directed Nutrition in ICU Patients
2017 EAT-ICU TRIAL: Early goal-directed nutrition versus standard of care in adult intensive care patients Single centre, blinded, randomised controlled trial Objective: To evaluate the...
EPICC Trial Summary: Intensive Physical Rehabilitation in Critically ill
2017 EPICC TRIAL Intensive versus standard physical rehabilitation therapy in the critically illl parallel-group, assessor-blinded, randomized controlled trial Objective: To determine improvement in long-term clinical...
ICE CUB 2 Trial Summary: Systematic ICU Triage in Critically Ill Patients
2017 ICE-CUB 2 TRIAL : Effect of systematic intensive care unit triage on long-term mortality among critically ill elderly patients in France Multicenter,cluster-randomized clinical trial...
CLASSIC Trial Summary: Restriction of IVF in Septic Shock
2022 CLASSIC TRIAL Restriction of Intravenous Fluid in ICU Patients with Septic Shock Multicenter, international, randomized controlled trial ca Objective: To investigate whether the restriction...
SHENFU Trial Summary: Shenfu Injection After in hospital Cardiac Arrest
2017 SHENFU TRIAL Efficacy and safety of combination therapy of Shenfu injection and post-resuscitation bundle in patients with return of spontaneous circulation(ROSC) after in-hospital cardiac...
TRANSFUSE Trial Summary: Age of RBCs for Transfusion in Critically Ill
2017 TRANSFUSE TRIAL Age of red cells(RBC) for transfusion and outcomes in critically ill adults Multicenter, randomized, double-blind trial Objective: To determine the effects of...
RECONNECT Trial Summary: Mechanical Ventilation After Successful Spontaneous Breathing Trial
2017 RECONNECT TRIAL Reconnection to mechanical ventilation (MV) for 1h after a successful spontaneous breathing trial (SBT) reduces reintubation in critically ill patients. Parallel, two-arm,...
LOVIT Trial Summary: IV Vitamin C in Septic Shock
2022 LOVIT TRIAL Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit Randomized, placebo-controlled trial Objective: To assess the use of intravenous...