Ob/Gyn

EMERGE Trial: Metformin in Gestational Diabetes

The EMERGE trial, published in JAMA in October 2023, is a pivotal study in the field of obstetric care, specifically targeting the management of gestational diabetes—a condition of elevated blood sugar that occurs during pregnancy. The trial’s goal was to … Read More

WOMAN Trial Summary: Early tranexamic acid in women with post-partum haemorrhage

WOMAN Trial: The Use of Tranexamic Acid in Reducing Death Due to Post-Partum Haemorrhage Post-partum haemorrhage (PPH) is a leading cause of maternal mortality worldwide. The administration of tranexamic acid has been shown to decrease bleeding-related deaths in trauma patients. … Read More

AGE Trial Summary: Mammogram Screening for Breast Cancer

AGE: Effect of mammographic screening from age 40 years on breast cancer mortality Multicenter, open label randomized comparative trial Objective: To assess if initiation of breast cancer screening with mammograms at age 40-41 reduces breast cancer mortality Women age 39-41 … Read More

WOMAN Trail Summary: Early tranexamic acid in post-partum hemorrhage

2018 WOMAN TRIAL Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage Randomised, double-blind, placebo-controlled trial Objective: To determine whether early administration of tranexamic acid reduces death from bleeding in women with … Read More

CHAP Trial Summary: Chronic Hypertension in Pregnancy

2022 CHAP TRIAL Treatment for Mild Chronic Hypertension during Pregnancy Open-label, multicenter, randomized trial Objective: To assess if treating mild chronic hypertension during pregnancy with a BP goal of <140/90 mmHg would lower incidence of adverse maternal and perinatal outcomes … Read More