CLASSIC Trial Summary: Restriction of IVF in Septic Shock
2022 CLASSIC TRIAL Restriction of Intravenous Fluid in ICU Patients with Septic Shock Multicenter, international, randomized controlled trial ca Objective: To investigate whether the restriction...
PRIME Care Trial Summary: Pharmacogenomic Testing for Drug-Gene Interactions in Depression Treatment
2022 PRIME CARE TRIAL Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection in Major Depressive Disorder Randomised, pragmatic, clinical trial Objective: To assess...
SHENFU Trial Summary: Shenfu Injection After in hospital Cardiac Arrest
2017 SHENFU TRIAL Efficacy and safety of combination therapy of Shenfu injection and post-resuscitation bundle in patients with return of spontaneous circulation(ROSC) after in-hospital cardiac...
TRANSFUSE Trial Summary: Age of RBCs for Transfusion in Critically Ill
2017 TRANSFUSE TRIAL Age of red cells(RBC) for transfusion and outcomes in critically ill adults Multicenter, randomized, double-blind trial Objective: To determine the effects of...
RECONNECT Trial Summary: Mechanical Ventilation After Successful Spontaneous Breathing Trial
2017 RECONNECT TRIAL Reconnection to mechanical ventilation (MV) for 1h after a successful spontaneous breathing trial (SBT) reduces reintubation in critically ill patients. Parallel, two-arm,...
LOVIT Trial Summary: IV Vitamin C in Septic Shock
2022 LOVIT TRIAL Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit Randomized, placebo-controlled trial Objective: To assess the use of intravenous...
Early Palliative Care in Patients with Lung Cancer Trial
2010 EARLY PALLIATIVE CARE M Early Palliative Care for Patients with Metastatic Non-Small-cell Lung Cancer Single-center, Prospective, non-blinded, parallel-group, randomized, control Objective: In patients with...
ACTION Trial: Anticoagulation in COVID-19
2021 ACTION TRIAL Therapeutic vs. prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer Pragmatic, open-label (with blinded adjudication), multicentre, randomised Objective:...
POISE-3 Trial Summary: Tranexamic Acid in Noncardiac Surgery
2022 POISE-3 TRIAL МІ Tranexamic Acid in Patients Undergoing Noncardiac Surgery International, randomized, controlled trial Objective: In patients undergoing noncardiac surgery who are at risk...
CHAP Trial Summary: Chronic Hypertension in Pregnancy
2022 CHAP TRIAL Treatment for Mild Chronic Hypertension during Pregnancy Open-label, multicenter, randomized trial Objective: To assess if treating mild chronic hypertension during pregnancy with...