REDECAP Trial Summary: High-Flow Oxygen for Tracheostomy Decannulation

REDECAP trial tracheostomy decannulation

2020 REDECAP TRIAL M High-flow oxygen with capping or suctioning for tracheostomy decannulation Multicentre randomised controlled trial So Objective: To compare an assessment of readiness for decannulation that is based on suctioning frequency with an assessment based on tracheostomy capping 330 patients Critically ill patients adult who had tracheostomy and were weaned from mechanical ventilation. 24hr Capping trial + Intermittent 02 (n=161) Suctioning + continuous 02 (n=169) PRIMARY OUTCOME Time to decannulation (in days) Diff 7; 95% CI, 5 to 9 SECONDARY OUTCOME 5.6 Decannulation failure % Diff 3.2; 95% CI, -1.2 to 8.1 2.4 16.8 Weaning failure % Diff 10.3; 95% CI, 3.4 to 17.4 6.5 9.9 Pneumonia % Diff 5.8; 95% CI, 0.2 to 11.8 Conclusion: Time to decannulation was shorter in those with decannulation based on suctioning frequency plus the use of continuous high-flow oxygen therapy than in those who received the standard of care with capping trials plus the use of intermittent high-flow oxygen therapy. H Martínez et al. NEJM 2020; 383:1009-17