2021
BASICS TRIAL
Endovascular therapy for stroke due to basilar-artery occlusion
multicenter, open-label, randomized controlled trial
M
Objective: To determine effectiveness of endovascular therapy in patients with stroke caused by basilar-artery occlusion.
300
patients.
Inclusion criteria: Patients aged ≥ 18 years with symptoms and signs compatible with ischemia in the basilar artery territory
مجھے
Endovascular therapy group
(n=154)
44.2
VS
Medical care group (n=146)
PRIMARY OUTCOME
Favorable outcome (modified Rankin Score of ≤3) at day 90% RR 1.18; 95% CI, 0.92 to 1.50
37.7
SECONDARY OUTCOMES
4.5
Symptomatic intracranial hemorrhage RR 6.9; 95% CI, 0.9 to 53.0
0.7
Mortality at 90 days
38.3
RR 0.87; 95% CI, 0.68 to 1.12
43.2
Conclusion: In patients with basilar-artery occlusion, endovascular therapy & medical therapy did not differ significantly with respect to a favorable functional outcome. Larger trials are needed to determine the efficacy and safety of endovascular therapy.
LCM Langezaal et al. NEJM 2021; 384:1910-1920 | Summary by Dr.Shreyash Bhoyar, MBBS
M Visualmed
