BASICS Trial: Endovascular Therapy for Basilar Stroke

2021 BASICS TRIAL Endovascular therapy for stroke due to basilar-artery occlusion multicenter, open-label, randomized controlled trial M Objective: To determine effectiveness of endovascular therapy in patients with stroke caused by basilar-artery occlusion. 300 patients. Inclusion criteria: Patients aged ≥ 18 years with symptoms and signs compatible with ischemia in the basilar artery territory مجھے Endovascular therapy group (n=154) 44.2 VS Medical care group (n=146) PRIMARY OUTCOME Favorable outcome (modified Rankin Score of ≤3) at day 90% RR 1.18; 95% CI, 0.92 to 1.50 37.7 SECONDARY OUTCOMES 4.5 Symptomatic intracranial hemorrhage RR 6.9; 95% CI, 0.9 to 53.0 0.7 Mortality at 90 days 38.3 RR 0.87; 95% CI, 0.68 to 1.12 43.2 Conclusion: In patients with basilar-artery occlusion, endovascular therapy & medical therapy did not differ significantly with respect to a favorable functional outcome. Larger trials are needed to determine the efficacy and safety of endovascular therapy. LCM Langezaal et al. NEJM 2021; 384:1910-1920 | Summary by Dr.Shreyash Bhoyar, MBBS M Visualmed