Tag: cholesterol

ALLHAT-LLT Trial Summary: Pravastatin in Moderate HLD

2002 ALLHAT-LLT Pravastatin vs Usual Care in Moderately Hypercholesterolemic, Hypertensive Patients Multicenter, randomized, nonblinded trial M Objective: To determine whether pravastatin compared with usual care reduces all-cause mortality in older, moderately hypercholes- terolemic, hypertensive participants with at least 1 additional CHD risk factor. Inclusion criteria: Ambulatory persons, aged 55 years or 10,355 older, with low-density […]

AIM-HIGH Trial: Niacin + Statins in Hyperlipidemia

2011 AIM-HIGH TRIAL Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy Placebo controlled, randomized clinical trial Σ Objective: To assess if extended-release niacin added to simvastatin to raise low levels of high-density lipoprotein (HDL) cholesterol is superior to simvastatin alone in reducing residual cardiovascular risk. 3,414 patients Inclusion criteria: patients with […]