BUCKLED Trial: US vs. XRay in Peds Forearm Fractures

The BUCKLED Trial: Ultrasound vs. Radiography in Pediatric Forearm Fractures In 2023, the BUCKLED Trial offered a novel perspective on diagnosing pediatric distal forearm fractures. This multicenter, open-label, noninferiority, randomized trial investigated whether ultrasonography could stand as a viable alternative … Read More

Baby-OSCAR: Ibuprofen in PDA

The Baby-OSCAR Trial: Evaluating Ibuprofen in Preterm Infants with PDA In 2024, the Baby-OSCAR Trial emerged as a pivotal study examining the effects of early treatment of patent ductus arteriosus (PDA) with ibuprofen in extremely preterm infants. This randomized, double-blind, … Read More

HEAL Trial Summary: Erythropoietin for Hypoxic–Ischemic Encephalopathy in Newborns

2022 HEAL TRIAL Trial of Erythropoietin for Hypoxic-Ischemic Encephalopathy in Newborns phase 3 double-blind, placebo-controlled, randomised controlled trial Objective: To assess the role of erythropoietin in conjunction with therapeutic hypothermia for neuroprotection in newborn infants with hypoxic-ischemic encephalopathy 501 Inclusion … Read More