
2017 REVIVE TRIAL Effectiveness of an exercise programme on physical function in patients discharged from hospital following critical illness. | Multicentre, prospective phase II, randomised controlled trial Objective: To investigate the effectiveness of a 6 week exercise programme in patients discharged home following critical illness compared with standard care 60 patients Inclusion criteria: Critically ill patients aged >18 years and mechanically ventilated for > 96 hours Exercise programme (n=30) Standard care (n=30) PRIMARY OUTCOME 6.8 SF-36: Physical functioning at 6-weeksHR 1.31; 95% CI, 0.95 to 1.80; P=0.09 Diff 3.0; 95% CI-2.2 to 8.2; P=0.26 SECONDARY OUTCOMES 12.0 SF-36: Role physical Diff 6.6; 95% CI 0.73 to 12.5; P=0.03 5.4 135.5 Incremental shuttle walk test (in metres) Diff 83.1; 95% CI 8.3 to 157.9; P=0.03 52.4 -7.8 Functional limitations profile: overall score Diff -4.8; 95% CI -8.7 to -0.9; P=0.02 -3.0 Conclusion: After discharge from hospital following critical illness, a 6 week individualised exercise programme did not improve self-reported physical fitness at 6 weeks or 6 months, although encouraging results in secondary outcomes should be used for further studies on this theory K McDowell et al. Thorax 2017;72:600-609