prevention

E3 Trial: Do e-Cigarettes Help Smokers Quit?

Published in JACC Advances, June 2025 The E3 Trial evaluated whether short-term use of nicotine or non-nicotine e-cigarettes, combined with counseling, improves smoking abstinence at 1 year. This multicenter, randomized controlled trial adds critical insight into smoking cessation strategies. 🧑‍⚕️ … Read More

Vitamin D to Prevent Cancer and CVD: VITAL Trial

VITAL Trial Vitamin D Summary The VITAL trial aimed to investigate whether supplementation with vitamin D reduces the risk of cancer or cardiovascular disease. It was a nationwide, randomized, placebo-controlled trial conducted with a two-by-two factorial design, including vitamin D3 … Read More

SECURE Trial Summary: Polypill Strategy in Secondary Cardiovascular Prevention

2022 SECURE TRIAL Polypill Strategy in Secondary Cardiovascular Prevention Phase 3, randomized, controlled clinical trial Objective: To evaluate the effect of polypill that includes key medications (aspirin, ramipril, and atorvastatin) on cardiovascular events in post-Ml patients. 2499 Inclusion criteria: Patients … Read More