2015 ICEREA TRIAL Endovascular versus external targeted temperature management for patients with out-of-hospital cardiac arrest multicenter, prospective, randomized controlled trial Objective: To evaluate if endovascular cooling is superior to external targeted temperature management in regards to favorable outcome after out-of-hospital cardiac arrest. 2 400 Inclusion criteria: Patients >18 to 79 years of age who had […]
Tag: targeted temperature management
TTM 48 Trial Summary: TTM for 48 hours in Cardiac Arrest
2017 2017 TTM 48 TRIAL M Targeted Temperature Management for 48 vs 24 hours and neurologic outcome after out-of-Hospital Cardiac Arrest (OOHCA) Multicenter,blinded,parallel,pragmatic,randomized superiority trial Objective: To determine neurologic outcomes with Targeted Temperature Management (TTM) at 33°C for 48 hours as compared with standard 24-hours. 355 Inclusion criteria: Adults aged 18-80 y with OOHCA with […]
ANTHARTIC Trial Summary: Prevention of Ventilator-Associated Pneumonia after Cardiac Arrest
2019 ANTHARTIC TRIAL M Prevention of early Ventilator-Associated Pneumonia after cardiac arrest Multicentre, randomised, double-blind, placebo-controlled Objective: To investigate whether in post out-of-hospital cardiac arrest (OOHCA) patients treated with targeted temperature management, does the use of empirical antibiotics prevent early ventilator-associated pneumonia. 194 patients Inclusion criteria: Patients > 18 years of age hospitalized in the […]