2015 SIMPLE TRIAL Cardioverter defibrillator implantation without induction of ventricular fibrillation multicentre, single-blind, non-inferiority, randomized controlled trial M Objective: To compare the efficacy & safety of ICD implantation without defibrillation testing versus the standard of ICD implantation with defibrillation testing 2500 Patients Inclusion criteria: Patients >18 years receiving their first Boston Scientific transvenous implantable cardioverter-defibrillator […]
Tag: ventricular fibrillation
ALIVE Trial Summary: Amiodarone or Lidocaine in VFib
2002 ALIVE TRIAL Amiodarone as Compared with Lidocaine for Shock-Resistant Ventricular Fibrillation Prospective, randomized, controlled, double-dummy trial Objective: To determine whether amiodarone compared with lidocaine could improve survival rates to hospital admission in patients with shock-refractory, out-of-hospital cardiac arrest. 344 adults with documented out-of-hospital ventricular fibrillation (VF); suffered persistent/recurrent VF despite three defibrillation shocks, epinephrine […]
ARREST Trial: ECMO-facilitated Resuscitation in Refractory Cardiac Arrest
2020 ARREST 2020 TRIAL M Advanced reperfusion strategies for patients with out-of hospital cardiac arrest (OHCA) and refractory ventricular fibrillation (VF) Phase 2, single center, open-label, randomized clinical trial Objective: To compare implementation of early ECMO facilitated resuscitation compared to standard ACLS resuscitation in adults suffering out of hospital cardiac arrest (OHCA) presenting with an […]