2021 FEISTY TRIAL Fibrinogen early in severe trauma study | multicentre, randomized controlled pilot study s Objective: To compare the time to fibrinogen replacement using f ibrinogen concentrate (FC) or cryoprecipitate (Cryo) in severely injured trauma patients with major hemorrhage & hypofibrinogenemia E 100 patients Inclusion criteria: Participants > 18 years with clinically significant hemorrhage […]
Tag: trauma
COBI Trial Summary: Hypertonic Saline in Traumatic Brain Injury
2021 COBI TRIAL M Effect of continuous infusion of hypertonic saline vs standard care on 6-month neurological outcomes in patients with traumatic brain injury multicenter, parallel-group, open-label, randomized clinical trial Objective: To assess whether continuous infusion of 20% hypertonic saline solution improves neurological outcome at 6 months in patients with moderate to severe TBI. 5 […]
Beta Blockers in Traumatic Brain Injury Trial Summary
2020 BETA-BLOCKER THERAPY IN TBI Beta-Blocker Therapy in Severe Traumatic Brain Injury (TBI) Single-center,non-blinded,randomized controlled trial d d Objective: To examine the effect of beta-blockers on outcomes in TBI patients. 154 patients Patients > 18 years with: -blunt head trauma & an intracranial injury with an AIS score of 3-5 requiring a surgical intervention within […]