Year: 2010 Title: CURRENT-OASIS 7 Subtitle: Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing PCI for ACS Type of Trial: Double-blind, Randomized Factorial Trial Objective: To evaluate whether a higher dosage of clopidogrel with aspirin (two … Read More
Cardiovascular Disease
FAST-TAVI II: Reducing LOS after TAVI
Year: 2024 Title: FAST-TAVI II Subtitle: Reducing length of stay after transfemoral transcatheter aortic valve implantation Type of Trial: A prospective, cluster, randomized, controlled trial Objective: To evaluate the efficacy and safety of an intervention (a training program) aimed to … Read More
VIVA Trial: TAVR in Severe AS and Small Annulus
The infographic summarizes the VIVA TRIAL as follows: Year: 2024 Title: VIVA TRIAL Subtitle: Transcatheter or Surgical Aortic Valve Replacement in Patients With Severe Aortic Stenosis and Small Aortic Annulus Type of Trial: A prospective, randomized, parallel, blinded trial Objective: … Read More
FULL REVASC Trial: FFR-Guided Complete PCI in MI
Year: 2024 Title: FULL REVASC Subtitle: FFR-Guided Complete or Culprit-Only PCI in Patients with Myocardial Infarction Type of Trial: A registry-based, randomized, parallel, blinded trial Objective: To evaluate the benefit of fractional flow reserve (FFR)–guided complete revascularization compared with usual … Read More
SMART Trial: TAVR in Small Aortic Annulus
Year: 2024 Title: SMART TRIAL Subtitle: Self-Expanding or Balloon-Expandable TAVR in Patients with a Small Aortic Annulus Type of Trial: A prospective, randomized controlled, post-market trial Objective: To generate clinical evidence on valve safety and performance of self-expanding (SE) versus … Read More
Beta Blockers After MI and Preserved EF
Year: 2024 Title: REDUCE-AMI Subtitle: Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction Type of Trial: A randomized, parallel-group, open-label trial Objective: To determine whether long-term treatment with oral beta-blockade in patients with myocardial infarction and preserved left ventricular systolic … Read More
EMPACT-MI: Empagliflozin after MI
Year: 2024 Title: EMPACT-MI Subtitle: Empagliflozin after Acute Myocardial Infarction Type of Trial: A double-blind, randomized, placebo-controlled trial Objective: To assess if the use of empagliflozin in the treatment of acute myocardial infarction (AMI) affects future mortality or heart failure … Read More
STEP-HFpEF DM: Semaglutide in HFpEF and DM
The study suggests that Semaglutide is effective in reducing symptoms and weight in patients with obesity-related heart failure with preserved ejection fraction and type 2 diabetes when compared to a placebo
PACER Trial: Platelet Transfusion before CVC Placement
The PACER Trial: Revisiting Platelet Transfusions for CVC Placement The 2023 PACER Trial investigated a critical aspect of clinical care involving patients with thrombocytopenia undergoing central venous catheter (CVC) placement. This parallel, single-blinded, randomized controlled trial aimed to establish whether … Read More
AGENT IDE: Paclitaxel-Coated Balloon for ISR
The AGENT IDE Trial: Revolutionizing the Treatment of In-Stent Restenosis The AGENT IDE Trial, a prominent study published in 2024, has shed light on a pivotal question in cardiology: Is a paclitaxel-coated balloon more effective than an uncoated balloon for … Read More