MADIT-CRT Trial Summary: CRT in HF
2009 MADIT-CRT TRIAL Cardiac-Resynchronization Therapy for the prevention of heart-failure events multicenter, open-label, randomized controlled trial Objective: To determine whether cardiac-resynchronization therapy with implantable cardioverter-defibrillator...
COACH Trial Summary: Access to Care in Heart Failure
2022 COACH TRIAL Trial of an intervention to improve acute heart failure outcomes cross-sectional, cluster-randomized trial M Objective: To determine the effectiveness of systematic use...
AF-CHF Trial Summary: Rhythm vs Rate Control for AFib and HF
AF-CHF: Rhythm Control versus Rate Control for Atrial Fibrillation and Heart Failure Multicenter, prospective, randomized, controlled trial Objective: To assess if rhythm-control reduce CV mortality...
PERSPECTIVE Trial Summary: Sacubitril/valsartan Effect on Cognition in HFpEF
2022 PERSPECTIVE TRIAL M Efficacy and safety of sacubitril/valsartan compared to valsartan on cognitive function in patients with chronic heart failure and preserved ejection fraction...
A-HEFT Trial Summary: Isosorbide Dinitrate and Hydralazine in Blacks with Heart Failure
2004 -0.1 3.1 A-HEFT TRIAL Combination of Isosorbide Dinitrate and Hydralazine in Blacks with Heart Failure Inclusion criteria: patients self-identified as 1,050 black (of African...
AATAC Trial Summary: Ablation vs. amiodarone for Persistent Atrial Fibrillation
2016 AATAC TRIAL Ablation vs. amiodarone for treatment of persistent atrial fibrillation in CHF Multicenter, parallel-group, open-label, randomized Objective: To assess if AF ablation is...
TAVR with Self-Expanding Prosthesis Trial Summary
2014 COREVALVE HIGH-RISK TRIAL Transcatheter aortic-valve replacement (TAVR) with a self-expanding prosthesis Multicenter, randomized, non inferiority trial “‘Objective: To compare TAVR using a self-expanding a...
ADVOR Trial Summary: Acetazolamide in Acute Decompensated Heart Failure with Volume Overload
2022 ADVOR STUDY Acetazolamide in acute decompensated heart failure with volume overload multicenter, parallel-group, double-blind, randomized, placebo-controlled trial a d Objective: To compare the incidence...
METEORIC-HF Trial Summary: Omecamtiv Mecarbil Effect of Exerciser in HFrEF
2022 METEORIC-HF Effect of Omecamtiv mecarbil on exercise capacity in chronic heart failure with reduced ejection fraction Phase 3, double-blind, placebo-controlled randomized trial a Objective:...
SODIUM-HF Trial Summary: Reduction of dietary sodium in Heart Failure
2022 SODIUM-HF TRIAL Reduction of dietary sodium to less than 100 mmol in heart failure International, open-label, randomised, controlled trial Objective: To evaluate if a...