clopidogrel

OPT-BIRISK Trial: Clopidogrel Monotherapy in High Risk ACS

Trial Title: OPT-BIRISKStudy Type: Multicenter, double-blind, randomized trial Objective: To determine if extended P2Y12 inhibitor monotherapy with clopidogrel is superior to ongoing dual antiplatelet therapy (DAPT) with aspirin and clopidogrel after 9 to 12 months of DAPT after PCI in … Read More

CURRENT-OASIS 7: Double Dose Clopidogrel or ASA in ACS

Year: 2010 Title: CURRENT-OASIS 7 Subtitle: Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing PCI for ACS Type of Trial: Double-blind, Randomized Factorial Trial Objective: To evaluate whether a higher dosage of clopidogrel with aspirin (two … Read More

ACTIVE W Trial Summary: Clopidogrel + ASA vs. OAC for Atrial Fibrillation

2006 ACTIVE W TRIAL Clopidogrel plus aspirin versus oral anticoagulation for atrial fibrillation Randomized, open treatment, controlled trial M Objective: Among patients with nonvalvular AF, how does combination aspirin/clopidogrel compare to warfarin in reducing the incidence of stroke, systemic embolism, … Read More

ACTIVE A Trial Summary: Clopidogrel + Aspirin in Atrial Fibrillation

2009 ACTIVE A TRIAL Effect of Clopidogrel Added to Aspirin in Patients with Atrial Fibrillation Multicenter, double-blind, parallel-group trial M Objective: To assess if the addition of clopidogrel to aspirin reduces the risk of vascular events compared to aspirin alone … Read More

ISAR-SAFE Trial Summary: 6 vs 12 months of DAPT after DES PCI

2015 ISAR-SAFE TRIAL M A randomized, double-blind, placebo-controlled trial of 6 vs. 12 months of clopidogrel therapy after drug-eluting stenting multicentre, double-blind, placebo-controlled, randomized controlled trial Objective: To compare the clinical outcome of 6 months of clopidogrel therapy to 12 … Read More

POPular AGE Trial Summary: Antiplatelet agent in NSTEMI

2020 POPULAR AGE TRIAL Clopidogrel versus ticagrelor or prasugrel in patients aged 70 years or older with non-ST-elevation acute coronary syndrome multicenter, randomized controlled trial Objective: To evaluate the effectiveness of clopidogrel compared with ticagrelor or prasugrel among patients ≥70 … Read More