The year 2025 brought several influential cardiovascular studies to light, and among the most promising was the DapaTAVI trial. This randomized, open-label trial explored the impact of dapagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, in a population often seen as high-risk … Read More
TAVR
ACE-PROTAVI Trial: Protamine Administration for Bleeding in TAVR
The Impact of Routine Protamine Administration in Transcatheter Aortic Valve Implantation (TAVI): Insights from the ACE-PROTAVI Trial As advancements in heart valve interventions continue, minimizing post-procedural complications remains a top priority for healthcare professionals. One area of growing interest is … Read More
FAST-TAVI II: Reducing LOS after TAVI
Year: 2024 Title: FAST-TAVI II Subtitle: Reducing length of stay after transfemoral transcatheter aortic valve implantation Type of Trial: A prospective, cluster, randomized, controlled trial Objective: To evaluate the efficacy and safety of an intervention (a training program) aimed to … Read More
VIVA Trial: TAVR in Severe AS and Small Annulus
The infographic summarizes the VIVA TRIAL as follows: Year: 2024 Title: VIVA TRIAL Subtitle: Transcatheter or Surgical Aortic Valve Replacement in Patients With Severe Aortic Stenosis and Small Aortic Annulus Type of Trial: A prospective, randomized, parallel, blinded trial Objective: … Read More
SMART Trial: TAVR in Small Aortic Annulus
Year: 2024 Title: SMART TRIAL Subtitle: Self-Expanding or Balloon-Expandable TAVR in Patients with a Small Aortic Annulus Type of Trial: A prospective, randomized controlled, post-market trial Objective: To generate clinical evidence on valve safety and performance of self-expanding (SE) versus … Read More
SCOPE I Trial Summary: Self-expanding vs Balloon Expandable Valve in TAVR
2019 SCOPE I TRIAL Safety and efficacy of a self-expanding versus a balloon-expandable bioprosthesis for transcatheter aortic valve replacement (TAVR) in patients with symptomatic severe aortic stenosis noninferiority, randomized controlled trial M Objective: To compare the safety and efficacy of … Read More
TAVR with Self-Expanding Prosthesis Trial Summary
2014 COREVALVE HIGH-RISK TRIAL Transcatheter aortic-valve replacement (TAVR) with a self-expanding prosthesis Multicenter, randomized, non inferiority trial “‘Objective: To compare TAVR using a self-expanding a transcatheter aortic-valve bioprosthesis, with surgical aortic-valve replacement in patients with severe aortic stenosis & an … Read More
UK TAVI Trial Summary: TAVI in Moderate Aortic Stenosis
2022 UK TAVI TRIAL M Effect of TAVI vs Surgical Aortic Valve Replacement on All-Cause Mortality in Patients With Aortic Stenosis Multicenter, randomized controlled trial – Objective: To assess if TAVI is non-inferior to surgical aortic valve replacement in patients … Read More