2020 ISCHEMIA TRIAL M Initial Invasive or Conservative Strategy for Stable Coronary Disease multicenter, parallel, randomized controlled trial Objective: Tto determine the effect of adding cardiac catheterization (hereafter, angiography) and revascularization when feasible to medical therapy in patients with stable coronary disease and moderate or severe ischemia 5,179 Patients Inclusion criteria: Patients >20 years of […]
Tag: coronary artery disease
ADAPTABLE Trial Summary: Aspirin Dosing in CV Disease
2013 ADAPTABLE TRIAL Comparative Effectiveness of Aspirin Dosing in Cardiovascular Disease Open-label, pragmatic design, randomized controlled trial M Objective: To assess whether a strategy of aspirin 325 mg/day would result in a lower risk of death from any cause, hospitalization for MI or hospitalization for stroke among patients with established atherosclerotic CV disease than a […]
ISCHEMIA-CKD Trial Summary: CAD Management in Advanced CKD
2020 ISCHEMIA-CKD TRIAL Management of coronary disease in patients with advanced kidney disease international, randomized controlled trial Objective: To compare the effectiveness of routine invasive therapy with optimal medical therapy among patients with stable coronary disease & advanced chronic kidney disease 777 Patients Inclusion criteria: Patients >20 years with at least moderate ischemia on noninvasive […]
POPULAR CABG Trial Summary: Ticagrelor in CABG
2020 POPULAR CABG TRIAL Effect of adding ticagrelor to standard aspirin on saphenous vein graft (SVG) patency in patients undergoing coronary artery bypass grafting double-blind, placebo-controlled, multicenter, randomized controlled trial M Objective: To assess whether ticagrelor added to standard aspirin Dimproves SVG patency among patients undergoing coronary artery bypass grafting (CABG) 499 Inclusion criteria: Patients […]