Category: Geriatrics

ACTION SENIORS Trial Summary: Exercise Program for Elderly

2019 ACTION SENIORS TRIAL Effect of a home-based exercise program on subsequent falls among community-dwelling high-risk older adults after a fall Parallel-group, single-blind, randomized clinical trial Objective: To assess the effect of a home-based exercise program as a fall prevention strategy in older adults who were referred to a fall prevention clinic after an index […]

65 Trial Summary: Vasopressors in Older Critically Ill Patients

2020 65 TRIAL Effect of Reduced Exposure to Vasopressors on 90-Day Mortality in Critically III patients Multicenter, pragmatic, randomized clinical trial Objective: To evaluate the effect on mortality at 90 days of reducing the exposure to vasopressors through permissive hypotension (mean arterial pressure target of 60-65 mm Hg) in intensive care unit (ICU) patients. 2,600 […]

REDUCE DELIRIUM Trial Summary: Haloperidol in Critically Ill at High Risk of Delirium

2017 2017 REDUCE-DELIRIUM TRIAL M Effect of haloperidol on survival among critically ill adults with a high risk of delirium | Randomized, double-blind, placebo-controlled trial Objective: To determine survival with prophylactic use of haloperidol among critically ill adults at high risk of delirium 1443 patients Inclusion criteria: Patients aged > 18 years without delirium and […]