Tag: depression

ANTLER Trial: Antidepressants in Primary care

 2021 ANTLER TRIAL Maintenance or discontinuation of antidepressants in primary care Multicenter, randomized, double-blind trial M Objective: To assess the effects of maintenance antidepressant therapy, as compared with discontinuation of treatment, in patients taking antidepressants 478 patients Inclusion criteria: Participants 18 to 74 years of age with >2 prior episodes of depression or took […]

PRIME Care Trial Summary: Pharmacogenomic Testing for Drug-Gene Interactions in Depression Treatment

2022 PRIME CARE TRIAL Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection in Major Depressive Disorder Randomised, pragmatic, clinical trial Objective: To assess if pharmacogenomic testing for drug-gene interactions affects the selection of antidepressant medication and response in patients with major depressive disorder (MDD)? 4 Patients with MDD who were initiating or switching […]