Understanding the PROMPT-AF Trial: A Breakthrough in Persistent AF Management The PROMPT-AF trial marks an important step forward in our understanding of how to manage persistent atrial fibrillation (AF) more effectively. Conducted as an investigator-initiated, multicenter, open-label randomized trial, PROMPT-AF … Read More
ablation
CASTLE HTx Trial: Ablation in HF and AFib
The CASTLE HTx trial, as published in the New England Journal of Medicine in 2023, was a single-center, open-label trial that aimed to determine the potential therapeutic effect of catheter ablation for symptomatic atrial fibrillation (AF) in patients with end-stage … Read More
ADVENT Trial: Pulse Field Ablation for AFib
The ADVENT trial, published in the New England Journal of Medicine in 2023, was a randomized, single-blind, noninferiority trial designed to compare the safety and efficacy of pulsed field ablation with conventional thermal ablation techniques (radiofrequency or cryoballoon) for the … Read More
Pioneering the Path: Key Landmark Trials on Ablation Procedures for Atrial Fibrillation
Delve into the pivotal clinical trials that have shaped our understanding and management of atrial fibrillation through ablation procedures. … Read More
APAF Trial: Ablation or Antiarrhythmics for PAF
2006 APAF STUDY A randomized trial of circumferential pulmonary vein ablation versus antiarrhythmic drug therapy in paroxysmal atrial fibrillation (AF) randomized controlled trial M Objective: To compare the relative efficacy of circumferential pulmonary vein ablation (CPVA) & antiarrhythmic drug … Read More
Surgical Ablation of AFib with MV Surgery
2015 SURGICAL ABLATION OF ATRIAL FIBRILLATION TRIAL Surgical ablation of atrial fibrillation during mitral-valve surgery parallel, randomized controlled trial M Objective: To evaluate treatment with mitral valve surgery plus ablation compared with mitral valve surgery alone among patients with mitral … Read More
AATAC Trial Summary: Ablation vs. amiodarone for Persistent Atrial Fibrillation
2016 AATAC TRIAL Ablation vs. amiodarone for treatment of persistent atrial fibrillation in CHF Multicenter, parallel-group, open-label, randomized Objective: To assess if AF ablation is superior to y amiodarone in patients with symptomatic (NYHA II-III) heart failure with reduced ejection … Read More