Tag: AKI

Albumin in Cirrhosis and SBP Clinical Trial

Effect of Intravenous Albumin on Renal Impairment and Mortality in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis Multi-center, open-label (analyst-blinded), randomised controlled trial Objective: To assess use of IV albumin for reducing renal impairment and mortality when compared to antibiotics alone in patients with cirrhosis and SBP. 126 Patients cirrhosis and SBP (PMN cell count […]

AKIKI 2 Trial Summary: RRT for Severe AKI

2021 AKIKI 2 TRIAL Comparison of two delayed strategies for renal replacement therapy initiation for severe AKI Multicentre, open-label, randomised, controlled trial Objective: To test the hypothesis that a more-delayed initiation strategy would result in more RRT-free days, compared with a delayed strategy. Σ 278 patients Inclusion criteria: critically ill patients with severe acute kidney […]

Cut-off Haemofiltration With Standard Haemofiltration in Acute Renal Failure

2018 HIGH VS STANDARD CUTOFF HEMOFILTRATION IN AKI A Double-Blind RCT of High cutoff versus Standard Hemofiltration in critically ill patients with Acute Kidney Injury (AKI) Single-center, double-blind, randomized controlled trial Objective: To assess impact of High cutoff hemofilter versus a Standard hemofilter on the median hours of noradrenaline-free time at day 7 in critically […]

SPARK Trial Summary: Furosemide in critically ill patients with early AKI

2017 SPARK TRIAL The effect of low-dose furosemide in critically illl patients with early acute kidney injury (AKI) Pilot, multicenter, randomized, double-blinded, placebo-controlled trial Objective: To evaluate the impact of furosemide in early AKI on worsening AKI, kidney recovery and RRT use as compared to placebo. 73 Patients > 18 years with RISK RIFLE category […]