2004 SAFE TRIAL A comparison of albumin and saline for fluid resuscitation in the intensive care unit multicenter, double-blind, randomized controlled trial M Objective: To compare the effect of fluid resuscitation with albumin as compared with saline on mortality in a heterogeneous population of patients in the ICU 6997 patients 目 Inclusion criteria: Patients ≥18 […]
Tag: albumin
Albumin in Cirrhosis and SBP Clinical Trial
Effect of Intravenous Albumin on Renal Impairment and Mortality in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis Multi-center, open-label (analyst-blinded), randomised controlled trial Objective: To assess use of IV albumin for reducing renal impairment and mortality when compared to antibiotics alone in patients with cirrhosis and SBP. 126 Patients cirrhosis and SBP (PMN cell count […]
ALBIOS Trial Summary: Albumin in Septic Shock
ALBUMIN REPLACEMENT IN PATIENTS WITH SEVERE SEPSIS OR SEPTIC SHOCK – THE ALBIOS TRIAL Multicenter, open-label, randomized trial Patients with severe sepsis 1,818 or septic shock were randomized to Albumin to maintain serum albumin ≥3 g/dL vs (n=910) No albumin (n=908) Mean follow-up: 90 Days PRIMARY OUTCOMES 31.8% All-cause mortality at 28 days P=0.94 41.1% […]