Tag: cardiovascular

POISE-3 Trial Summary: Tranexamic Acid in Noncardiac Surgery

2022 POISE-3 TRIAL МІ Tranexamic Acid in Patients Undergoing Noncardiac Surgery International, randomized, controlled trial Objective: In patients undergoing noncardiac surgery who are at risk for bleeding and CV events, does tranexamic acid lowers incidence of major bleeding when compared to placebo and is it noninferior to placebo with respect to the incidence of major […]

CHAP Trial Summary: Chronic Hypertension in Pregnancy

2022 CHAP TRIAL Treatment for Mild Chronic Hypertension during Pregnancy Open-label, multicenter, randomized trial Objective: To assess if treating mild chronic hypertension during pregnancy with a BP goal of <140/90 mmHg would lower incidence of adverse maternal and perinatal outcomes than a strategy of withholding treatment until the BP was 160/105 mm Hg or higher […]