WOEST Trial Summary The WOEST trial, a groundbreaking study published in The Lancet, has shed light on a significant issue faced by patients undergoing percutaneous coronary intervention (PCI) while taking oral anticoagulants. Traditionally, triple therapy involving aspirin and clopidogrel has been recommended, but it comes with an increased risk of severe bleeding. The trial aimed […]
Tag: PCI
BRIGHT-4 Trial Summary: Bivalirudin in STEMI
2022 BRIGHT-4 TRIAL Bivalirudin plus a high-dose infusion versus heparin monotherapy in patients with STEMI undergoing primary PCI investigator-initiated, open-label, randomized controlled trial Objective: To evaluate the safety and efficacy of a high-dose infusion of bivalirudin after primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) compared with unfractionated heparin 6016 […]
SECURE PCI Trial Summary: Loading Atorvastatin in ACS
2018 SECURE-PCI TRIAL Effect of loading dose of atorvastatin prior to planned percutaneous coronary intervention on major adverse cardiovascular events in acute coronary syndrome double-blind, multicenter, randomized controlled trial Objective: To determine if periprocedural loading doses of atorvastatin decrease 30-day major adverse cardiovascular events (MACE) in patients with ACS and planned invasive management 4191 Patients […]
AIDA Trial Summary: Bioabsorbable Scaffolds for Routine PCI
2017 AIDA TRIAL Bioresorbable scaffolds versus metallic stents in routine PCI Prospective, multi-center, single-blind, randomized controlled trial M Objective: To assess if bioresorbable scaffolds superior to standard drug-eluting stents (DES) with regard to target-vessel failure in patients with stable or unstable CAD undergoing PCI 1,845 Inclusion criteria: patients with stable or unstable patients coronary artery […]
TRANSFER AMI Trial Summary: Early Angioplasty after Fibrinolysis for Acute MI
2009 TRANSFER-AMI trial: Routine Early Angioplasty after Fibrinolysis for Acute Myocardial Infarction Multicenter, randomized, non-blinded, parallel Assignment Objective: To assess outcomes in patients with AMI treated with thrombolysis transferring to a center providing PCI for standard treatment (rescue PCI or delayed angiography) vs immediate transfer within 6 hours of fibrinolysis 1059 Patients > 18 years […]