Explore the transformative clinical trials that have solidified the role of SGLT2 inhibitors in heart failure management and their potential to redefine the treatment landscape. Introduction Heart failure is a complex clinical syndrome associated with significant morbidity and mortality. In recent years, sodium-glucose cotransporter-2 (SGLT2) inhibitors have emerged as a promising new class of drugs […]
Tag: empagliflozin
EMPULSE Trial Summary: Empagliflozin in Acute Heart Failure
2021 EMPULSE TRIAL Empagliflozin in patients hospitalized for Acute Heart Failure Randomized, parallel trial Objective: To evaluate empagliflozin compared with placebo among patients with acute decompensated heart failure. 530 patients Inclusion criteria: Patients hospitalized for acute HF regardless of ejection fraction or diabetes status & following stabilization criteria; NT-proBNP >1600 pg/ml or BNP 2400 pg/ml […]