Tag: empagliflozin

A New Frontier in Heart Failure Management: A Comprehensive Review of Landmark Clinical Trials on SGLT2 Inhibitors

Explore the transformative clinical trials that have solidified the role of SGLT2 inhibitors in heart failure management and their potential to redefine the treatment landscape. Introduction Heart failure is a complex clinical syndrome associated with significant morbidity and mortality. In recent years, sodium-glucose cotransporter-2 (SGLT2) inhibitors have emerged as a promising new class of drugs […]

EMPULSE Trial Summary: Empagliflozin in Acute Heart Failure

2021 EMPULSE TRIAL Empagliflozin in patients hospitalized for Acute Heart Failure Randomized, parallel trial Objective: To evaluate empagliflozin compared with placebo among patients with acute decompensated heart failure. 530 patients Inclusion criteria: Patients hospitalized for acute HF regardless of ejection fraction or diabetes status & following stabilization criteria; NT-proBNP >1600 pg/ml or BNP 2400 pg/ml […]