Tag: ROSC

TAME Trial: Mild Hypercapnia after Cardiac Arrest

TAME Trial Summary The TAME trial investigated the impact of mild hypercapnia versus normocapnia on neurologic outcomes in adults with coma who were resuscitated after out-of-hospital cardiac arrest. Current guidelines recommend normocapnia, but mild hypercapnia has been suggested to enhance cerebral blood flow and potentially improve neurologic outcomes. The trial randomly assigned adults admitted to […]

VAM-IHCA Trial Summary: Vasopressin and Methylprednisolone on ROSC after Cardiac Arrest

2021 VAM-IHCA TRIAL M Effect of Vasopressin and Methylprednisolone vs Placebo on Return of Spontaneous Circulation in Patients with In-Hospital Cardiac Arrest Multicenter, randomized, double-blind, placebo-controlled trial Objective: To determine whether the combination of vasopressin and methylprednisolone administered during in-hospital cardiac arrest improves return of spontaneous circulation. 512 patients Inclusion criteria: Patients >18 years of […]

SHENFU Trial Summary: Shenfu Injection After in hospital Cardiac Arrest

2017 SHENFU TRIAL Efficacy and safety of combination therapy of Shenfu injection and post-resuscitation bundle in patients with return of spontaneous circulation(ROSC) after in-hospital cardiac arrest Prospective,randomized controlled clinical study Objective:To evaluate the efficacy,safety & improvement in mortality of combined therapy of Shenfu injection & post-resuscitation care bundle among in-hospital cardiac arrest patients 978 patients […]