Tag: placebo

VAM-IHCA Trial Summary: Vasopressin and Methylprednisolone on ROSC after Cardiac Arrest

Post author By admin
Post date July 23, 2022
Categories In Cardiovascular Disease, Critical Care

2021 VAM-IHCA TRIAL M Effect of Vasopressin and Methylprednisolone vs Placebo on Return of Spontaneous Circulation in Patients with In-Hospital Cardiac Arrest Multicenter, randomized, double-blind, placebo-controlled trial Objective: To determine whether the combination of vasopressin and methylprednisolone administered during in-hospital cardiac arrest improves return of spontaneous circulation. 512 patients Inclusion criteria: Patients >18 years of […]

ATACAS Trial Summary: Tranexamic Acid in Coronary Artery Surgery

Post author By admin
Post date July 23, 2022
Categories In Cardiovascular Disease, Surgery

2017 ATACAS TRIAL: Tranexamic Acid in patients undergoing coronary artery surgery Multicenter,2×2 factorial design, double-blind, randomized controlled trial Objective: To evaluate death risk and thrombotic complications with TXA among at-risk patients undergoing coronary artery surgery. 4662 Inclusion criteria: Patients >18 years of age undergoing elective coronary artery surgery either on or off pump & at […]

MIDAS Trial Summary: Midodrine for Vasopressor Weaning

Post author By admin
Post date July 22, 2022
Categories In Critical Care

2020 MIDAS TRIAL: Effect of midodrine versus placebo on time to vasopressor discontinuation in patients with persistent hypotension in the intensive care unit Multi-centre, randomised, double-blind, placebo-controlled trial Objective: To investigate whether the administration of midodrine, an oral al-adrenergic agonist, as adjunct to standard treatment shortens the duration of intravenous vasopressor requirement 132 Hypotensive patients […]