Tag: sedation

POKER Trial Summary: Propofol or Ketofol for Procedural Sedation

2016 POKER TRIAL Propofol or Ketofol for procedural sedation and analgesia in emergency medicine Randomised, double-blind clinical trial Objective: To determine whether an emergency physician-provided deep sedation with 1:1 combination of ketamine & propofol (ketofol) resulted in fewer adverse respiratory events requiring intervention than propofol alone for procedural sedation and analgesia 573 Inclusion criteria: Adult […]

NONSEDA Trial Summary: Sedation in Critically Ill Intubated Patients

2020 NONSEDA TRIAL M Nonsedation or light sedation in critically ill, mechanically ventilated patients Investigator-initiated, randomised, clinical, parallel-group, multinational, superiority trial . a 5 Objective: To assess whether in critically ill, mechanically ventilated patients, does a strategy of no sedation, as compared with light sedation with daily sedation breaks, impact day 90 mortality. 192 patients […]