TIME Trial Summary: Morning vs. Evening dose of Antihypertensives
2022 TIME TRIAL Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK prospective, open-label, blinded-endpoint, randomized controlled...
SUPPORT Trial Summary: Olmesartan in CHF
2015 SUPPORT TRIAL M Clinical impacts of additive use of olmesartan in hypertensive patients with chronic heart failure (CHF) prospective, open-label, randomized controlled trial Objective:...
AIM-HIGH Trial: Niacin + Statins in Hyperlipidemia
2011 AIM-HIGH TRIAL Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy Placebo controlled, randomized clinical trial Σ Objective: To assess if...
AGE Trial Summary: Mammogram Screening for Breast Cancer
AGE: Effect of mammographic screening from age 40 years on breast cancer mortality Multicenter, open label randomized comparative trial Objective: To assess if initiation of...
NORDICC Trial Summary: Colonoscopy for Colorectal Cancer Screening
2022 NORDICC TRIAL Effect of colonoscopy screening on risks of colorectal cancer and related death pragmatic, multicenter, randomized controlled trial Objective: To investigate the effects...
ACCOMPLISH Trial: Benazepril + Amlodipine or HCTZ for Hypertension
2008 ACCOMPLISH TRIAL Benazepril plus Amlodipine or Hydrochlorothiazide for Hypertension in High-Risk Patients Multi-centered, double-blind, randomized, controlled trial Objective: To evaluate the effect of amlodipine...
ACCORD BP Trial Summary: Intensive BP Control in Type 2 Diabetes
2010 ACCORD BP TRIAL Effects of intensive blood-pressure control in type 2 diabetes mellitus Multicenter, randomized, controlled, open-label trial Objective: In patients with T2DM at...
SODIUM-HF Trial Summary: Reduction of dietary sodium in Heart Failure
2022 SODIUM-HF TRIAL Reduction of dietary sodium to less than 100 mmol in heart failure International, open-label, randomised, controlled trial Objective: To evaluate if a...
PRECISE Trial Summary: Pregabalin for Acute and Chronic Sciatica
2017 PRECISE TRIAL Trial of pregabalin for acute and chronic sciatica Randomized, double-blind, placebo-controlled trial Objective: To determine whether pregabalin reduces the intensity of sciatica...
VITAL Trial: Vitamin D and Incident Fractures
2022 VITAL TRIAL Supplemental Vitamin D and Incident Fractures in Midlife and Older Adults double-blind, placebo-controlled, 2×2 factorial, randomized controlled trial Objective: To investigate the...