ANDROMEDA SHOCK Trial: Resuscitation in Septic Shock
ANDROMEDA-SHOCK: Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels in Septic Shock Multicenter, randomized trial conducted at 28 intensive care...
VICTAS Trial: Vitamin C, Thiamine, and Hydrocortisone in Sepsis
2021 VICTAS TRIAL IM Effect of vitamin C, thiamine, and hydrocortisone on ventilator-and vasopressor-free days in patients with sepsis multicenter, double-blind, randomized controlled trial Objective:...
ALBIOS Trial Summary: Albumin in Septic Shock
ALBUMIN REPLACEMENT IN PATIENTS WITH SEVERE SEPSIS OR SEPTIC SHOCK – THE ALBIOS TRIAL Multicenter, open-label, randomized trial Patients with severe sepsis 1,818 or septic...
ADRENAL Trial Summary: Steroids in Septic Shock
ADJUNCTIVE GLUCOCORTICOID THERAPY IN PATIENTS WITH SEPTIC SHOCK – THE ADRENAL TRIAL Multicenter, double-blind, parallel-group, randomized, controlled trial 3,658 patients with septic shock requiring vasopressors...
ACTS Trial: Ascorbic acid, Steroids and Thiamine in Septic Shock
2020 ACTS TRIAL Effect of ascorbic acid, corticosteroids, and thiamine on organ injury in septic shock Multicenter, randomized, blinded, placebo-controlled superiority trial M Objective: To...
CLASSIC Trial Summary: Restriction of IVF in Septic Shock
2022 CLASSIC TRIAL Restriction of Intravenous Fluid in ICU Patients with Septic Shock Multicenter, international, randomized controlled trial ca Objective: To investigate whether the restriction...
LOVIT Trial Summary: IV Vitamin C in Septic Shock
2022 LOVIT TRIAL Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit Randomized, placebo-controlled trial Objective: To assess the use of intravenous...