VITAL-AF Trial Summary The VITAL-AF trial aimed to determine whether point-of-care screening with a handheld single-lead ECG device during primary care visits increases the diagnosis of atrial fibrillation (AF) in older adults. The study randomized 16 primary care clinics in a 1:1 ratio, with half implementing AF screening using the AliveCor KardiaMobile device during vital […]
Category: Electrophysiology
WRAP-IT Trial: Utilizing Antibiotic-Eluting Envelopes to Reduce Infections After Cardiac Device Implantation
WRAP-IT Trial Summary Infections following the placement of cardiac implantable electronic devices (CIEDs) can lead to significant morbidity and mortality. Although preoperative antibiotics are a standard prophylactic strategy, evidence for other preventive approaches is limited. The WRAP-IT trial sought to examine the efficacy and safety of an absorbable, antibiotic-eluting envelope in reducing CIED-associated infections. The […]
MADIT-CRT Trial Summary: CRT in HF
2009 MADIT-CRT TRIAL Cardiac-Resynchronization Therapy for the prevention of heart-failure events multicenter, open-label, randomized controlled trial Objective: To determine whether cardiac-resynchronization therapy with implantable cardioverter-defibrillator (CRT-ICD) would reduce the risk of death or heart-failure events in M patients with mild cardiac symptoms, reduced ejection fraction, and wide QRS complex. 1820 patients Inclusion criteria: Patients aged […]