WHiTE 5 Trial Summary The WHiTE5 trial, a multicenter, randomized, controlled trial, has provided valuable insights into the use of bone cement in hip fractures treated with hemiarthroplasty. The trial aimed to compare the health-related quality of life and outcomes of patients undergoing cemented versus uncemented hemiarthroplasty for intracapsular hip fractures in individuals aged 60 […]
Tag: surgery
ALLIANCE Trial Summary: Axillary Dissection in Breast Cancer
2020 ALLIANCE TRIAL Effect of axillary dissection vs no axillary dissection on 10-year overall survival among women with invasive breast cancer and sentinel node metastasis Multicenter, phase 3, randomized controlled trial M Objective: To determine whether the 10-year overall survival of patients with sentinel lymph node metastases treated with breast-conserving therapy and sentinel lymph node […]
ATACAS Trial Summary: Tranexamic Acid in Coronary Artery Surgery
2017 ATACAS TRIAL: Tranexamic Acid in patients undergoing coronary artery surgery Multicenter,2×2 factorial design, double-blind, randomized controlled trial Objective: To evaluate death risk and thrombotic complications with TXA among at-risk patients undergoing coronary artery surgery. 4662 Inclusion criteria: Patients >18 years of age undergoing elective coronary artery surgery either on or off pump & at […]
DREAMS Trial Summary: Dexamethasone for Post-op Nausea and Vomiting
2017 DREAMS TRIAL Dexamethasone vs standard treatment for postoperative nausea and vomiting (PONV) in gastrointestinal surgery Pragmatic, blinded, multicentre,randomised controlled trial Objective: To determine reduction in PONV by preoperative Dexamethasone in patients undergoing elective bowel surgery & its association with other measurable benefits during recovery from surgery. 1350 patients Inclusion criteria: Adults over 18 years […]