The MATTERHORN trial, published in The New England Journal of Medicine, investigates the efficacy of transcatheter repair (M-TEER) versus surgical mitral-valve repair for secondary mitral regurgitation (MR) in patients with heart failure. This randomized controlled trial included 208 patients, equally … Read More
surgery
WHiTE 5 Trial Summary: Cemented or Uncemented Hemiarthroplasty for Hip Fracture
WHiTE 5 Trial Summary The WHiTE5 trial, a multicenter, randomized, controlled trial, has provided valuable insights into the use of bone cement in hip fractures treated with hemiarthroplasty. The trial aimed to compare the health-related quality of life and outcomes … Read More
ALLIANCE Trial Summary: Axillary Dissection in Breast Cancer
2020 ALLIANCE TRIAL Effect of axillary dissection vs no axillary dissection on 10-year overall survival among women with invasive breast cancer and sentinel node metastasis Multicenter, phase 3, randomized controlled trial M Objective: To determine whether the 10-year overall survival … Read More
ATACAS Trial Summary: Tranexamic Acid in Coronary Artery Surgery
2017 ATACAS TRIAL: Tranexamic Acid in patients undergoing coronary artery surgery Multicenter,2×2 factorial design, double-blind, randomized controlled trial Objective: To evaluate death risk and thrombotic complications with TXA among at-risk patients undergoing coronary artery surgery. 4662 Inclusion criteria: Patients >18 … Read More
DREAMS Trial Summary: Dexamethasone for Post-op Nausea and Vomiting
2017 DREAMS TRIAL Dexamethasone vs standard treatment for postoperative nausea and vomiting (PONV) in gastrointestinal surgery Pragmatic, blinded, multicentre,randomised controlled trial Objective: To determine reduction in PONV by preoperative Dexamethasone in patients undergoing elective bowel surgery & its association with … Read More