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VAM-IHCA Trial Summary: Vasopressin and Methylprednisolone on ROSC after Cardiac Arrest

July 23, 2022
2021 VAM-IHCA TRIAL M Effect of Vasopressin and Methylprednisolone vs Placebo on Return of Spontaneous Circulation in Patients with In-Hospital Cardiac Arrest Multicenter, randomized, double-blind,...

CHECK-UP Trial Summary: Ramped vs Sniffing Position for Intubation

July 23, 2022
2017 CHECK-UP: POSITION- Ramped position vs Sniffing position during endotracheal intubation of critically ill adults 2 x 2 factorial design,randomised, multicentre,pragmatic trial 9 5 Objective:...

ATACAS Trial Summary: Tranexamic Acid in Coronary Artery Surgery

July 23, 2022
2017 ATACAS TRIAL: Tranexamic Acid in patients undergoing coronary artery surgery Multicenter,2×2 factorial design, double-blind, randomized controlled trial Objective: To evaluate death risk and thrombotic...

MIDAS Trial Summary: Midodrine for Vasopressor Weaning

July 22, 2022
2020 MIDAS TRIAL: Effect of midodrine versus placebo on time to vasopressor discontinuation in patients with persistent hypotension in the intensive care unit Multi-centre, randomised,...

EAT-ICU Trial Summary: Early Goal-Directed Nutrition in ICU Patients

July 22, 2022
2017 EAT-ICU TRIAL: Early goal-directed nutrition versus standard of care in adult intensive care patients Single centre, blinded, randomised controlled trial Objective: To evaluate the...

EPICC Trial Summary: Intensive Physical Rehabilitation in Critically ill

July 22, 2022
2017 EPICC TRIAL Intensive versus standard physical rehabilitation therapy in the critically illl parallel-group, assessor-blinded, randomized controlled trial Objective: To determine improvement in long-term clinical...

DREAMS Trial Summary: Dexamethasone for Post-op Nausea and Vomiting

July 19, 2022
2017 DREAMS TRIAL Dexamethasone vs standard treatment for postoperative nausea and vomiting (PONV) in gastrointestinal surgery Pragmatic, blinded, multicentre,randomised controlled trial Objective: To determine reduction...

ICE CUB 2 Trial Summary: Systematic ICU Triage in Critically Ill Patients

July 19, 2022
2017 ICE-CUB 2 TRIAL : Effect of systematic intensive care unit triage on long-term mortality among critically ill elderly patients in France Multicenter,cluster-randomized clinical trial...

INPRESS Trial Summary: Blood Pressure Management in Patients Undergoing Major Surgery

July 19, 2022
2017 INPRESS TRIAL Effect of individualized vs standard blood pressure management strategies on postoperative organ dysfunction among high-risk patients undergoing major surgery. Multicenter, randomized, parallel-group...

TRANSFER AMI Trial Summary: Early Angioplasty after Fibrinolysis for Acute MI

July 17, 2022
2009 TRANSFER-AMI trial: Routine Early Angioplasty after Fibrinolysis for Acute Myocardial Infarction Multicenter, randomized, non-blinded, parallel Assignment Objective: To assess outcomes in patients with AMI...

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