AFFIRM Trial Summary: Rate vs Rhythm Control for AFib

AFFIRM Trial: A Comparison of Rate Control and Rhythm Control in Patients with Atrial Fibrillation Multicenter, parallel-group, randomized, controlled trial Objective: Among patients with atrial...

ADRENAL Trial Summary: Steroids in Septic Shock

ADJUNCTIVE GLUCOCORTICOID THERAPY IN PATIENTS WITH SEPTIC SHOCK – THE ADRENAL TRIAL Multicenter, double-blind, parallel-group, randomized, controlled trial 3,658 patients with septic shock requiring vasopressors...

ACCORD Trial: Intensive Glucose Lowering in DM2

ACCORD: Effects of Intensive Glucose Lowering in Type 2 Diabetes Multicenter, double-blinded, two-by-two factorial, randomized controlled trial Objective: To assess if intensive glycemic control targeting...

ACTT-1 Trial Summary: Remdesivir in Covid-19

2020 ACTT-1 TRIAL Remdesivir for the Treatment of Covid-19 Double-blind, randomized, placebo-controlled trial Objective: To evaluate the clinical efficacy and safety of putative investigational therapeutic...

ACT Trial Summary: Acetylcysteine before Angiography

ACETYLCYSTEINE FOR PREVENTION OF RENAL OUTCOMES IN PATIENTS UNDERGOING ANGIOGRAPHY – ACT TRIAL Multicenter, Double-blind, Randomized, Placebo-controlled Trial STUDY OBJECTIVE: To Assess the use of...

ACTT-4 Trial Summary: Baricitinib in Covid-19

2022 ACTT-4 TRIAL Baricitinib versus dexamethasone for adults hospitalised with COVID-19 double-blind, double placebo-controlled, randomised controlled trial M Objective: To compare baricitinib in combination with...