Cardiac Surgery

Surgical Ablation of AFib with MV Surgery

2015 SURGICAL ABLATION OF ATRIAL FIBRILLATION TRIAL Surgical ablation of atrial fibrillation during mitral-valve surgery parallel, randomized controlled trial M Objective: To evaluate treatment with mitral valve surgery plus ablation compared with mitral valve surgery alone among patients with mitral … Read More

SCOPE I Trial Summary: Self-expanding vs Balloon Expandable Valve in TAVR

2019 SCOPE I TRIAL Safety and efficacy of a self-expanding versus a balloon-expandable bioprosthesis for transcatheter aortic valve replacement (TAVR) in patients with symptomatic severe aortic stenosis noninferiority, randomized controlled trial M Objective: To compare the safety and efficacy of … Read More

AIMS Trial Summary: Irbesartan in Marfan Syndrome

2019 AIMS TRIAL Irbesartan in Marfan syndrome Placebo-controlled, double-blind randomised trial Objective: To evaluate an angiotensin receptor blocker (ARB) compared with placebo among patients with confirmed Marfan syndrome. 192 patients Inclusion criteria: Patients with clinically confirmed Marfan syndrome, 6-40 years … Read More

ISCHEMIA-CKD Trial Summary: CAD Management in Advanced CKD

2020 ISCHEMIA-CKD TRIAL Management of coronary disease in patients with advanced kidney disease international, randomized controlled trial Objective: To compare the effectiveness of routine invasive therapy with optimal medical therapy among patients with stable coronary disease & advanced chronic kidney … Read More

POPULAR CABG Trial Summary: Ticagrelor in CABG

2020 POPULAR CABG TRIAL Effect of adding ticagrelor to standard aspirin on saphenous vein graft (SVG) patency in patients undergoing coronary artery bypass grafting double-blind, placebo-controlled, multicenter, randomized controlled trial M Objective: To assess whether ticagrelor added to standard aspirin … Read More

AVATAR Trial Summary: AVR in Asymptomatic Severe Aortic Stenosis

2021 AVATAR TRIAL M Aortic Valve replacement versus Conservative treatment in asymptomatic severe Aortic Stenosis Parallel, Randomised controlled trial Objective: To evaluate aortic valve replacement (AVR) compared with conservative therapy among patients with asymptomatic severe aortic stenosis 157 Inclusion criteria: … Read More

PALACS Trial Summary: Posterior Left Pericardiotomy for Post-op AFib

2021 PALACS TRIAL M Posterior left pericardiotomy for the prevention of postoperative atrial fibrillation after cardiac surgery Randomized, parallel, stratified, single-centre study Objective: To evaluate posterior left pericardiotomy compared with no intervention among patients undergoing open heart surgery 420 patients … Read More