DEVICE Trial Summary The article discusses the findings of the DEVICE trial, which aimed to determine whether video laryngoscopy increased the likelihood of successful tracheal intubation on the first attempt compared to direct laryngoscopy in critically ill adults. The trial … Read More
Anesthesiology
SERVE HF Trial Summary: Adaptive sero-ventilation for CSA in HF
2015 SERVE-HF TRIAL M Adaptive servo-ventilation for central sleep apnea in systolic heart failure parallel, randomized controlled trial Objective: To assess the effectiveness of adaptive servo-ventilation Damong subjects with heart failure with reduced ejection fraction and central sleep apnea 1315 … Read More
PRECISE Trial Summary: Pregabalin for Acute and Chronic Sciatica
2017 PRECISE TRIAL Trial of pregabalin for acute and chronic sciatica Randomized, double-blind, placebo-controlled trial Objective: To determine whether pregabalin reduces the intensity of sciatica as compared to placebo 209 Inclusion criteria: Sciatica patients aged > 18 years having: – … Read More
POKER Trial Summary: Propofol or Ketofol for Procedural Sedation
2016 POKER TRIAL Propofol or Ketofol for procedural sedation and analgesia in emergency medicine Randomised, double-blind clinical trial Objective: To determine whether an emergency physician-provided deep sedation with 1:1 combination of ketamine & propofol (ketofol) resulted in fewer adverse respiratory … Read More
REDECAP Trial Summary: High-Flow Oxygen for Tracheostomy Decannulation
2020 REDECAP TRIAL M High-flow oxygen with capping or suctioning for tracheostomy decannulation Multicentre randomised controlled trial So Objective: To compare an assessment of readiness for decannulation that is based on suctioning frequency with an assessment based on tracheostomy capping … Read More
LOCO2 Trial Summary: Oxygen Therapy in ARDS
2020 2020 LOCO2 TRIAL M Liberal or conservative oxygen therapy for Acute Respiratory Distress Syndrome Multicentre, randomised controlled trial Objective: To assess whether in patients with Acute Respiratory Distress Syndrome (ARDS), does conservative (Target PaO2:55-70mmHg; SpO2: 88-92%) vs. liberal (Target … Read More
ANTHARTIC Trial Summary: Prevention of Ventilator-Associated Pneumonia after Cardiac Arrest
2019 ANTHARTIC TRIAL M Prevention of early Ventilator-Associated Pneumonia after cardiac arrest Multicentre, randomised, double-blind, placebo-controlled Objective: To investigate whether in post out-of-hospital cardiac arrest (OOHCA) patients treated with targeted temperature management, does the use of empirical antibiotics prevent early … Read More
NONSEDA Trial Summary: Sedation in Critically Ill Intubated Patients
2020 NONSEDA TRIAL M Nonsedation or light sedation in critically ill, mechanically ventilated patients Investigator-initiated, randomised, clinical, parallel-group, multinational, superiority trial . a 5 Objective: To assess whether in critically ill, mechanically ventilated patients, does a strategy of no sedation, … Read More
CHECK-UP Trial Summary: Ramped vs Sniffing Position for Intubation
2017 CHECK-UP: POSITION- Ramped position vs Sniffing position during endotracheal intubation of critically ill adults 2 x 2 factorial design,randomised, multicentre,pragmatic trial 9 5 Objective: To evaluate the reduction in incidence of oxygen desaturation in ramped position as compared to … Read More