Category: Critical Care

SAFE Trial Summary: Albumin or Saline in ICU

2004 SAFE TRIAL A comparison of albumin and saline for fluid resuscitation in the intensive care unit multicenter, double-blind, randomized controlled trial M Objective: To...

ALBIOS Trial Summary: Albumin in Septic Shock

ALBUMIN REPLACEMENT IN PATIENTS WITH SEVERE SEPSIS OR SEPTIC SHOCK – THE ALBIOS TRIAL Multicenter, open-label, randomized trial Patients with severe sepsis 1,818 or septic...

ADRENAL Trial Summary: Steroids in Septic Shock

ADJUNCTIVE GLUCOCORTICOID THERAPY IN PATIENTS WITH SEPTIC SHOCK – THE ADRENAL TRIAL Multicenter, double-blind, parallel-group, randomized, controlled trial 3,658 patients with septic shock requiring vasopressors...

ACURASYS Trial Summary: NM blockers in ARDS

2010 ACURASYS TRIAL Neuromuscular Blockers in Early Acute Respiratory Distress Syndrome Multicenter, double-blinded, placebo-controlled trial Objective: To assess if administration of cisatracurium improve survival when...

BOX Trial Summary: BP Target in OHCA

2022 BOX TRIAL: BP TARGETS IN OHCA Blood-pressure targets in comatose survivors of cardiac arrest Investigator-initiated, double-blind, superiority, 2×2 factorial design, randomized clinical trial Objective:...