BOX Trial Summary: Oxygen Targets in Comatose Survivors of Cardiac Arrest
2022 BOX TRIAL: OXYGEN TARGETS IN OHCA Oxygen targets in comatose survivors of cardiac arrest Investigator-initiated, open-label, superiority,2×2 factorial design, randomized clinical trial Objective: To...
BOX Trial Summary: BP Target in OHCA
2022 BOX TRIAL: BP TARGETS IN OHCA Blood-pressure targets in comatose survivors of cardiac arrest Investigator-initiated, double-blind, superiority, 2×2 factorial design, randomized clinical trial Objective:...
SMART-MED Trial Summary: Balanced Crystalloids versus Saline in Critically Ill
2018 SMART-MED & SMART-SURG TRIAL Balanced crystalloids versus saline in critically ill adults Pragmatic, unblinded, cluster-randomized, multiple-crossover trial Objective: To determine whether administration of balanced...
PARTNER Trial Summary: Family-Support Intervention in ICU
2018 PARTNER TRIAL A Randomized trial of a Family-support intervention in intensive care units Multicenter, stepped-wedge, cluster-randomized trial Objective: To compare a multicomponent family-support intervention...
REVIVE Trial Summary: Exercise Program in Critically Ill after Discharge
2017 REVIVE TRIAL Effectiveness of an exercise programme on physical function in patients discharged from hospital following critical illness. | Multicentre, prospective phase II, randomised...
REDUCE DELIRIUM Trial Summary: Haloperidol in Critically Ill at High Risk of Delirium
2017 2017 REDUCE-DELIRIUM TRIAL M Effect of haloperidol on survival among critically ill adults with a high risk of delirium | Randomized, double-blind, placebo-controlled trial...
PLUS Trial Summary: Balanced Multielectrolyte Solution in Critically Ill
2022 PLUS TRIAL Balanced multi electrolyte solution versus saline in critically ill adults Investigator initiated, double-blind, parallel-group, randomised controlled trial d a Objective: To assess...
TTM 48 Trial Summary: TTM for 48 hours in Cardiac Arrest
2017 2017 TTM 48 TRIAL M Targeted Temperature Management for 48 vs 24 hours and neurologic outcome after out-of-Hospital Cardiac Arrest (OOHCA) Multicenter,blinded,parallel,pragmatic,randomized superiority trial...
ATESS Trial Summary: Vitamin C + Thiamine for Septic Shock
2020 ATESS TRIAL Combination therapy of vitamin C and thiamine for septic shock Multicentre, double-blind, randomized controlled trial Objective: To evaluate the effects of early...
PSP Trial Summary: Interventional Treatment for Spontaneous Pneumothorax
2020 PSP TRIAL M Conservative versus interventional treatment for spontaneous pneumothorax Prospective, randomized control, non-inferiority trial Objective: To assess whether conservative management compared to interventional...