The BUCKLED Trial: Ultrasound vs. Radiography in Pediatric Forearm Fractures In 2023, the BUCKLED Trial offered a novel perspective on diagnosing pediatric distal forearm fractures. This multicenter, open-label, noninferiority, randomized trial investigated whether ultrasonography could stand as a viable alternative … Read More
Blog
Baby-OSCAR: Ibuprofen in PDA
The Baby-OSCAR Trial: Evaluating Ibuprofen in Preterm Infants with PDA In 2024, the Baby-OSCAR Trial emerged as a pivotal study examining the effects of early treatment of patent ductus arteriosus (PDA) with ibuprofen in extremely preterm infants. This randomized, double-blind, … Read More
AGENT IDE: Paclitaxel-Coated Balloon for ISR
The AGENT IDE Trial: Revolutionizing the Treatment of In-Stent Restenosis The AGENT IDE Trial, a prominent study published in 2024, has shed light on a pivotal question in cardiology: Is a paclitaxel-coated balloon more effective than an uncoated balloon for … Read More
REDUCE LAP-HF II: Atrial Shunt Device in HFpEF and HFmEF
Insights from the REDUCE LAP-HF II Trial: Atrial Shunt Devices in Heart Failure Management The REDUCE LAP-HF II Trial, published in 2022, was a significant randomized, blinded, sham-controlled trial aiming to enhance the treatment for patients with heart failure. It … Read More
ILUMIEN IV: OCT-Guided vs. Angio-Guided PCI
Unveiling the ILUMIEN IV Trial: A New Era of Percutaneous Coronary Intervention The ILUMIEN IV: OPTIMAL PC Trial, conducted in 2023, is a landmark study that compares the efficacy of Optical Coherence Tomography (OCT)-guided coronary stent implantation to the traditional … Read More
BYPASS-CTCA: CT Angio before Cath in Patients with CABG
The BYPASS-CTCA Trial: Enhancing Cardiac Procedures with Pre-Operative CT Scans In 2023, the BYPASS-CTCA Trial set out to redefine the pre-operative protocol for patients with a history of coronary artery bypass grafting (CABG). This open-label randomized controlled trial posed a … Read More
DCD HEART Trial: Transplant in Circulatory Death
Pioneering Cardiac Care: Results from the DCD HEART Trial The DCD HEART Trial has broken new ground in the field of heart transplantation, examining the outcomes with donor hearts after circulatory death—a method that could potentially increase the donor pool … Read More
RUBY Trial Summary: Dostarlimab for Endometrial Cancer
The RUBY Trial: A New Chapter in Endometrial Cancer Treatment Recent results from the RUBY Trial have introduced a significant advancement in the treatment of primary advanced or recurrent endometrial cancer. The phase 3, randomized, double-blind trial meticulously evaluated the … Read More
BEST Trial Summary: Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass
The BEST Trial: Pioneering Insights into Bariatric Surgery Outcomes The groundbreaking ‘BEST Trial’ (Bariatric Surgery Comparative Trial) has offered a fresh perspective on the effectiveness and safety of two prominent bariatric procedures: Sleeve Gastrectomy (SG) and Roux-en-Y Gastric Bypass (RYGB). … Read More
ARTESIA Trial: Apixaban for Subclinical AFib
ARTESIA Trial Summary The ARTESIA trial, which stands for “Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation,” was a landmark study aimed at comparing the efficacy and safety of apixaban versus aspirin in patients with subclinical atrial fibrillation (AF). The … Read More