A pneumothorax (collapsed lung) occurs when air enters the pleural space, disrupting normal lung expansion. Early recognition and appropriate management are critical to prevent progression to tension pneumothorax, a life-threatening emergency. This post breaks down the systematic approach to pneumothorax … Read More
Cardiac Surgery
FARES-II Trial: PCC vs FFP in Cardiac Surgery
FARES-II Trial: PCC Outperforms Frozen Plasma in Managing Coagulopathic Bleeding During Cardiac Surgery In the FARES-II trial, researchers investigated whether Prothrombin Complex Concentrate (PCC) could offer superior outcomes compared to frozen plasma for patients undergoing cardiac surgery who develop coagulopathic … Read More
ARIES-HM3 Trial: Aspirin + VKA in LVAD
Visual Abstract Summary for the ARIES-HM3 Trial Question Can aspirin be safely excluded from an antithrombotic regimen, including a vitamin K antagonist (VKA), in patients with a fully magnetically levitated LVAD, and does this reduce nonsurgical bleeding complications? Design Key … Read More
FAST-TAVI II: Reducing LOS after TAVI
Year: 2024 Title: FAST-TAVI II Subtitle: Reducing length of stay after transfemoral transcatheter aortic valve implantation Type of Trial: A prospective, cluster, randomized, controlled trial Objective: To evaluate the efficacy and safety of an intervention (a training program) aimed to … Read More
VIVA Trial: TAVR in Severe AS and Small Annulus
The infographic summarizes the VIVA TRIAL as follows: Year: 2024 Title: VIVA TRIAL Subtitle: Transcatheter or Surgical Aortic Valve Replacement in Patients With Severe Aortic Stenosis and Small Aortic Annulus Type of Trial: A prospective, randomized, parallel, blinded trial Objective: … Read More
BYPASS-CTCA: CT Angio before Cath in Patients with CABG
The BYPASS-CTCA Trial: Enhancing Cardiac Procedures with Pre-Operative CT Scans In 2023, the BYPASS-CTCA Trial set out to redefine the pre-operative protocol for patients with a history of coronary artery bypass grafting (CABG). This open-label randomized controlled trial posed a … Read More
DCD HEART Trial: Transplant in Circulatory Death
Pioneering Cardiac Care: Results from the DCD HEART Trial The DCD HEART Trial has broken new ground in the field of heart transplantation, examining the outcomes with donor hearts after circulatory death—a method that could potentially increase the donor pool … Read More
Surgical Ablation of AFib with MV Surgery
2015 SURGICAL ABLATION OF ATRIAL FIBRILLATION TRIAL Surgical ablation of atrial fibrillation during mitral-valve surgery parallel, randomized controlled trial M Objective: To evaluate treatment with mitral valve surgery plus ablation compared with mitral valve surgery alone among patients with mitral … Read More
SCOPE I Trial Summary: Self-expanding vs Balloon Expandable Valve in TAVR
2019 SCOPE I TRIAL Safety and efficacy of a self-expanding versus a balloon-expandable bioprosthesis for transcatheter aortic valve replacement (TAVR) in patients with symptomatic severe aortic stenosis noninferiority, randomized controlled trial M Objective: To compare the safety and efficacy of … Read More
AIMS Trial Summary: Irbesartan in Marfan Syndrome
2019 AIMS TRIAL Irbesartan in Marfan syndrome Placebo-controlled, double-blind randomised trial Objective: To evaluate an angiotensin receptor blocker (ARB) compared with placebo among patients with confirmed Marfan syndrome. 192 patients Inclusion criteria: Patients with clinically confirmed Marfan syndrome, 6-40 years … Read More