Understanding the Impact of PCI in Stable Angina: Insights from the ORBITA-2 Trial The ORBITA-2 trial has emerged as a cornerstone study in the field of cardiology, particularly in the treatment of stable angina through Percutaneous Coronary Intervention (PCI). This … Read More
Cardiovascular Disease
T-PASS Trial: A Shift in Post-Stenting Treatment for ACS
T-PASS Trial Summary The management of Acute Coronary Syndrome (ACS) after stenting has been a hot topic for medical researchers for years. The recent T-PASS Trial in 2023 has shed light on the possible advantages of shifting from the conventional … Read More
RITA 3 Trial: Interventional vs. Conservative Strategy in UA/NSTEMI
RITA 3 Trial Summary Background: Methods: Findings: Interpretation: Key Takeaways: Source
ELAN Trial: Early vs. Later Initiation of DOAC in Acute Ischemic Stroke and Atrial Fibrillation
ELAN Trial Summary Introduction:The ELAN trial aimed to investigate the optimal timing of initiating direct oral anticoagulants (DOACs) in individuals with atrial fibrillation (AF) who had experienced an acute ischemic stroke. The study compared early anticoagulation (initiated within 48 hours … Read More
DIGAMI 2 Trial: Insulin-Based Glucose Control in Type 2 Diabetic Patients Following MI
DIGAMI 2 Trial Summary Introduction:The DIGAMI 2 trial aimed to evaluate the effect of insulin-based glucose control in type 2 diabetic patients following myocardial infarction compared to conventional management at similar levels of glucose control. The study investigated three treatment … Read More
Vitamin D to Prevent Cancer and CVD: VITAL Trial
VITAL Trial Vitamin D Summary The VITAL trial aimed to investigate whether supplementation with vitamin D reduces the risk of cancer or cardiovascular disease. It was a nationwide, randomized, placebo-controlled trial conducted with a two-by-two factorial design, including vitamin D3 … Read More
VOYAGER PAD Trial: Rivaroxaban in PAD after Revascularization
VOYAGER PAD Trial Summary The VOYAGER PAD trial aimed to assess the efficacy and safety of rivaroxaban, a factor Xa inhibitor, in patients with peripheral artery disease (PAD) who had undergone lower-extremity revascularization. Patients with PAD who have undergone revascularization … Read More
WARFASA Trial: Aspirin for Preventing the Recurrence of VTE
WARFASA Trial Summary The WARFASA trial aimed to evaluate the effectiveness of aspirin in preventing recurrent venous thromboembolism (VTE) in patients who had previously experienced an unprovoked VTE event. Approximately 20% of patients with unprovoked VTE experience a recurrence within … Read More
WASID Trial Summary: Warfarin and Aspirin for Symptomatic Intracranial Arterial Stenosis
WASID Trial Summary The WASID trial sought to compare the effectiveness of warfarin and aspirin in the treatment of atherosclerotic intracranial arterial stenosis, a significant cause of stroke. While warfarin is often preferred over aspirin for this condition, the two … Read More
WOEST Trial Summary: Clopidogrel with or without aspirin in patients taking oral anticoagulant therapy and undergoing PCI
WOEST Trial Summary The WOEST trial, a groundbreaking study published in The Lancet, has shed light on a significant issue faced by patients undergoing percutaneous coronary intervention (PCI) while taking oral anticoagulants. Traditionally, triple therapy involving aspirin and clopidogrel has … Read More