Year: 2024 Title: FAST-TAVI II Subtitle: Reducing length of stay after transfemoral transcatheter aortic valve implantation Type of Trial: A prospective, cluster, randomized, controlled trial Objective: To evaluate the efficacy and safety of an intervention (a training program) aimed to … Read More
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CodeBreak 300 Trial: Sotorasib + Panitumumab in CRC
Year: 2023 Title: CodeBreaK 300 Subtitle: Sotorasib plus Panitumumab in Refractory Colorectal Cancer with Mutated KRAS G12C Type of Trial: A phase 3 randomized, open-label, active-controlled trial Objective: To compare progression-free survival in previously treated participants with KRAS G12C mutated … Read More
VIVA Trial: TAVR in Severe AS and Small Annulus
The infographic summarizes the VIVA TRIAL as follows: Year: 2024 Title: VIVA TRIAL Subtitle: Transcatheter or Surgical Aortic Valve Replacement in Patients With Severe Aortic Stenosis and Small Aortic Annulus Type of Trial: A prospective, randomized, parallel, blinded trial Objective: … Read More
CAROLINA Trial: Linagliptin vs. Glimepiride in T2DM
Year: 2019 Title: CAROLINA TRIAL Subtitle: Effect of Linagliptin vs Glimepiride on Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes Type of Trial: An International, Randomised, Parallel Group, Double Blind Trial Objective: To assess cardiovascular outcomes of linagliptin … Read More
AiDAPT Trial: Automated Insulin Delivery in Pregnancy Complicated by T1DM
Year: 2023 Title: AiDAPT TRIAL Subtitle: Automated Insulin Delivery in Women with Pregnancy Complicated by Type 1 Diabetes Type of Trial: Interventional, randomized controlled trial Objective: To find definitive proof of a benefit to women by using automated closed-loop for … Read More
FULL REVASC Trial: FFR-Guided Complete PCI in MI
Year: 2024 Title: FULL REVASC Subtitle: FFR-Guided Complete or Culprit-Only PCI in Patients with Myocardial Infarction Type of Trial: A registry-based, randomized, parallel, blinded trial Objective: To evaluate the benefit of fractional flow reserve (FFR)–guided complete revascularization compared with usual … Read More
SMART Trial: TAVR in Small Aortic Annulus
Year: 2024 Title: SMART TRIAL Subtitle: Self-Expanding or Balloon-Expandable TAVR in Patients with a Small Aortic Annulus Type of Trial: A prospective, randomized controlled, post-market trial Objective: To generate clinical evidence on valve safety and performance of self-expanding (SE) versus … Read More
Beta Blockers After MI and Preserved EF
Year: 2024 Title: REDUCE-AMI Subtitle: Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction Type of Trial: A randomized, parallel-group, open-label trial Objective: To determine whether long-term treatment with oral beta-blockade in patients with myocardial infarction and preserved left ventricular systolic … Read More
EMPACT-MI: Empagliflozin after MI
Year: 2024 Title: EMPACT-MI Subtitle: Empagliflozin after Acute Myocardial Infarction Type of Trial: A double-blind, randomized, placebo-controlled trial Objective: To assess if the use of empagliflozin in the treatment of acute myocardial infarction (AMI) affects future mortality or heart failure … Read More
STEP-HFpEF DM: Semaglutide in HFpEF and DM
The study suggests that Semaglutide is effective in reducing symptoms and weight in patients with obesity-related heart failure with preserved ejection fraction and type 2 diabetes when compared to a placebo