FIESTY Trial Summary: Fibrinogen in Severe Trauma
2021 FEISTY TRIAL Fibrinogen early in severe trauma study | multicentre, randomized controlled pilot study s Objective: To compare the time to fibrinogen replacement using...
COBI Trial Summary: Hypertonic Saline in Traumatic Brain Injury
2021 COBI TRIAL M Effect of continuous infusion of hypertonic saline vs standard care on 6-month neurological outcomes in patients with traumatic brain injury multicenter,...
ATACAS Trial Summary: Tranexamic Acid in Coronary Artery Surgery
2017 ATACAS TRIAL: Tranexamic Acid in patients undergoing coronary artery surgery Multicenter,2×2 factorial design, double-blind, randomized controlled trial Objective: To evaluate death risk and thrombotic...
DREAMS Trial Summary: Dexamethasone for Post-op Nausea and Vomiting
2017 DREAMS TRIAL Dexamethasone vs standard treatment for postoperative nausea and vomiting (PONV) in gastrointestinal surgery Pragmatic, blinded, multicentre,randomised controlled trial Objective: To determine reduction...
INPRESS Trial Summary: Blood Pressure Management in Patients Undergoing Major Surgery
2017 INPRESS TRIAL Effect of individualized vs standard blood pressure management strategies on postoperative organ dysfunction among high-risk patients undergoing major surgery. Multicenter, randomized, parallel-group...
POISE-3 Trial Summary: Tranexamic Acid in Noncardiac Surgery
2022 POISE-3 TRIAL МІ Tranexamic Acid in Patients Undergoing Noncardiac Surgery International, randomized, controlled trial Objective: In patients undergoing noncardiac surgery who are at risk...