2010 ACCORD BP TRIAL Effects of intensive blood-pressure control in type 2 diabetes mellitus Multicenter, randomized, controlled, open-label trial Objective: In patients with T2DM at high risk for CV events, does intensive BP control (SBP <120 mmHg) reduce rates of … Read More
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3SITES Trial Summary: Central Venous Catheterization Insertion Site
2015 3SITES TRIAL Intravascular complications of central venous catheterization by insertion site Multicenter, randomized controlled trial Objective: To evaluate the risk of catheter related bloodstream infection or symptomatic catheter related deep-vein thrombosis in an adult patient who had been admitted … Read More
3CPO Trial Summary: Noninvasive Ventilation in Pulmonary Edema
2008 3CPO TRIAL Noninvasive Ventilation in Acute Cardiogenic Pulmonary Edema multicenter, open, prospective, randomized, controlled trial Objective: To determine whether noninvasive ventilation reduces mortality and whether there are important differences in outcome associated with the method of treatment (CPAP or … Read More
Visualmed App Update 2.9.9 – Upcoming New Features
Usama bin Nasir, MDFounder of Visualmed App
TAVR with Self-Expanding Prosthesis Trial Summary
2014 COREVALVE HIGH-RISK TRIAL Transcatheter aortic-valve replacement (TAVR) with a self-expanding prosthesis Multicenter, randomized, non inferiority trial “‘Objective: To compare TAVR using a self-expanding a transcatheter aortic-valve bioprosthesis, with surgical aortic-valve replacement in patients with severe aortic stenosis & an … Read More
BOX Trial Summary: Oxygen Targets in Comatose Survivors of Cardiac Arrest
2022 BOX TRIAL: OXYGEN TARGETS IN OHCA Oxygen targets in comatose survivors of cardiac arrest Investigator-initiated, open-label, superiority,2×2 factorial design, randomized clinical trial Objective: To evaluate the appropriate oxygen target for mechanical ventilation in comatose survivors of out-of-hospital cardiac arrest … Read More
BOX Trial Summary: BP Target in OHCA
2022 BOX TRIAL: BP TARGETS IN OHCA Blood-pressure targets in comatose survivors of cardiac arrest Investigator-initiated, double-blind, superiority, 2×2 factorial design, randomized clinical trial Objective: To evaluate the appropriate blood pressure target in comatose survivors of out-of-hospital cardiac arrest 789 … Read More
AXIOMATIC-TKR Trial Summary: Milvexian for the Prevention of VTE
2022 AXIOMATIC-TKR TRIAL Milvexian for the prevention of Venous thromboembolism Parallel-group, Open-label, randomized controlled trial Objective: To compare the efficacy & safety of milvexian and enoxaparin in patients undergoing elective knee arthroplasty 1242 patients INCLUSION CRITERIA: Patients undergoing unilateral total … Read More
ADVOR Trial Summary: Acetazolamide in Acute Decompensated Heart Failure with Volume Overload
2022 ADVOR STUDY Acetazolamide in acute decompensated heart failure with volume overload multicenter, parallel-group, double-blind, randomized, placebo-controlled trial a d Objective: To compare the incidence of successful decongestion with addition of acetazolamide vs placebo to loop diuretic therapy in patients … Read More
METEORIC-HF Trial Summary: Omecamtiv Mecarbil Effect of Exerciser in HFrEF
2022 METEORIC-HF Effect of Omecamtiv mecarbil on exercise capacity in chronic heart failure with reduced ejection fraction Phase 3, double-blind, placebo-controlled randomized trial a Objective: To determine whether omecamtiv mecarbil, a novel direct myosin activator improves peak exercise capacity in … Read More